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Recombinant Human Flt3-Ligand

类型:细胞因子及添加物
品牌:PeproTech
种属:Human
应用:WB,ELISA,Functional

规格: 2μg

货号: 300-19-2

价格: ¥1195.00

规格: 10μg

货号: 300-19-10

价格: ¥2913.00

规格: 50μg

货号: 300-19-50

价格: ¥10225.00

规格: 100μg

货号: 300-19-100

价格: ¥17044.00

规格: 250μg

货号: 300-19-250

价格: ¥29832.00

规格: 500μg

货号: 300-19-500

价格: ¥44312.00

规格: 1mg

货号: 300-19-1000

价格: ¥68288.00

数量:

产品规格

种属

Human

已发表种属

Hamster, Human, Mouse, Non-human primate, Rabbit, Rat

Expression System

E. coli

氨基酸序列

TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA

分子量

17.6 kDa

分类

Recombinant

类型

Protein

纯度

≥ 98% by SDS-PAGE gel and HPLC analyses.

内毒素浓度

<1 EU/µg

活性

The ED50 was determined by the dose-dependent stimulation of the proliferation of human AML5 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg.

偶联物

Unconjugated

形式

Lyophilized

纯化类型

purified

内含物

no preservative

保存条件

-20°C

运输条件

Ambient

 

产品详细信息

Recombinant Human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues.

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

 

靶标信息

FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.

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