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Recombinant Human R-Spondin-1

类型:细胞因子及添加物
品牌:PeproTech
种属:Human

规格: 5μg

货号: 120-38-5

价格: ¥1195.00

规格: 20μg

货号: 120-38-20

价格: ¥2913.00

规格: 100μg

货号: 120-38-100

价格: ¥13355.00

规格: 250μg

货号: 120-38-250

价格: ¥22928.00

规格: 500μg

货号: 120-38-500

价格: ¥34078.00

规格: 1mg

货号: 120-38-1000

价格: ¥52018.00

数量:

产品规格

种属

Human

已发表种属

Bovine, Dog, Human, Mouse, Pig, Xenopus

Expression System

CHO cells

氨基酸序列

SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR RRKGQQQQQQ QGTVGPLTSA GPA

分子量

26.7 kDa

分类

Recombinant

类型

Protein

纯度

≥ 95% by SDS-PAGE gel and HPLC analyses.

内毒素浓度

<1 EU/µg

活性

R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 is 1.0-3.0 ug/ml.

偶联物

Unconjugated

形式

Lyophilized

纯化类型

purified

内含物

no preservative

保存条件

-20°C

运输条件

Ambient

 

产品详细信息

120-38-1MG will be provided as 2 x 500 µg (120-38-500UG).

Recombinant Human R-Spondin-1 is a 26.7 kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions.

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

 

靶标信息

This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.

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